DISCOVERY OF A NOVEL RORΓ ANTAGONIST WITH SKIN-RESTRICTED EXPOSURE FOR TOPICAL TREATMENT OF MILD TO MODERATE PSORIASIS

ABSTRACT Clinical success of IL-17/IL-23 pathway biologics for the treatment of moderate to severe psoriasis suggests that targeting...

DISCOVERY, OPTIMIZATION, AND EVALUATION OF NON-BILE ACID FXR/TGR5 DUAL AGONISTS

ABSTRACT Although several potent bile acid Farnesoid X receptor and Takeda G-protein-coupled receptor 5 dual agonists such as INT-767...

 
 
 

ENHANCED THERMAL STABILITY AND LARGE PIEZOELECTRIC PROPERTIES OF SM-DOPED PBO 3 -PBO 3 -PBTIO 3 MULTIFUNCTIONAL CERAMICS

Abstract The crystal structure, electric properties, thermal stability and optical properties of Sm-doped 0.15PbO 3 -0.50PbO 3 -0.35PbTiO...

POLY-BASED COMPOSITE FILM WITH AG-IMMOBILIZED TEMPO-OXIDIZED NANO-TEA CELLULOSE FOR IMPROVING PHOTOCATALYTIC PERFORMANCE

Abstract In the present study, we report a simple and eco-friendly method for the synthesis and immobilization of silver nanoparticles...

 
 
 

POLY MONOFILAMENTS FOR BIODEGRADABLE BRAIDED SELF-EXPANDING STENT

Abstract Although poly is the widely used material for bioresorbable stents, publications on PLLA braided stents are still lacking....

EFFECT OF I-PHASE MORPHOLOGY AND MICROSTRUCTURE TRANSFORMATION IN BIOMEDICAL MG-3ZN-1MN-1Y ALLOYS ON VITRO DEGRADATION BEHAVIOR IN DYNAMIC SIMULATED BODY FLUID

Abstract The corrosion mechanism of as-cast, heat-treated and extruded Mg-3Zn-1Mn-1Y alloys with different microstructure is investigated...

 
 
 

WINNING GENE COMBINATION TAKES ALL

Researchers have traced the remaining last steps of the biological pathway that gives oats resistance to the deadly crop disease take-all.

CELL CYTOSKELETON AS TARGET FOR NEW ACTIVE AGENTS

Through a unique combination of computer simulations and laboratory experiments, researchers have discovered new binding sites for...

 
 
 

VALIDATION ENGINEER - THERMO FISHER SCIENTIFIC - CARLSBAD, CA

Support manufacturing laboratory equipment implementation including but not limited to IOPQs, user requirement specifications, traceability...

ADCOMM EXPERTS SPLIT ON WHETHER TO APPROVE CHEMOCENTRYX'S AVACOPAN

Adcomm experts split on whether to approve ChemoCentryx's avacopan ntaylor Fri, 05/07/2021 - 06:49

 
 
 

GENE THERAPY BIOTECH GYROSCOPE FINDS UNNAVIGABLE SEAS ON IPO MARKET

Gene therapy biotech Gyroscope finds unnavigable seas on IPO market aarmstrong Fri, 05/07/2021 - 09:50

EVIDENCE FOR THE PREFERENTIAL REUSE OF SUB‐DOMAIN MOTIFS IN PRIMORDIAL PROTEIN FOLDS

Abstract A comparison of protein backbones makes clear that not more than approximately 1400 different folds exist, each specifying...

 
 
 

SCIENCE 37 TAPS A SPAC TO GO PUBLIC, WITH SITELESS TRIAL SPECIALIST VALUED AT A COOL $1B

Science 37 taps a SPAC to go public, with siteless trial specialist valued at a cool $1B badams Fri, 05/07/2021 - 04:15

GALAPAGOS CUTS PIPELINE, TARGETS €150M IN SAVINGS AFTER SETBACKS

Galapagos cuts pipeline, targets €150M in savings after setbacks ntaylor Fri, 05/07/2021 - 06:07

 
 
 

SCSNV: ACCURATE DSCRNA-SEQ SNV CO-EXPRESSION ANALYSIS USING DUPLICATE TAG COLLAPSING

Identifying single nucleotide variants has become common practice for droplet-based single-cell RNA-seq experiments; however, presently,...

SENIOR BIOSTATISTICIAN - LEICA BIOSYSTEMS - VISTA, CA

Participate in development of database clinical trial data specifications, including eCRF design, user requirements, edit rules/checks,...

 
 
 

SYSTEMATIC INTERROGATION OF MUTATION GROUPINGS REVEALS DIVERGENT DOWNSTREAM EXPRESSION PROGRAMS WITHIN KEY CANCER GENES

Genes implicated in tumorigenesis often exhibit diverse sets of genomic variants in the tumor cohorts within which they are frequently...

NUTRACEUTICAL AND THERAPEUTIC POTENTIAL OF PHYCOCYANOBILIN FOR TREATING ALZHEIMER'S DISEASE

Abstract Alzheimer's disease is a devastating neurodegenerative condition provoking the loss of cognitive and memory performances....

 
 
 

VIRTUAL PAR-A-THON WORKSHOP

The IEEE Engineering in Medicine and Biology Standards Committee & IEEE SA Healthcare & Life Sciences Practice invites you to participate...

TRACKING DOWN THE TINIEST OF FORCES: HOW T CELLS DETECT INVADERS

What happens on a molecular level, when our immune system detects antigens? Scientists have found out, how T cells exert tiny forces...

 
 
 





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