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DETOKI IDENTIFIES AND CHARACTERIZES THE DYNAMICS OF CHROMATIN TAD-LIKE DOMAINS IN A SINGLE CELL

Topologically associating domains are a key structure of the 3D mammalian genomes. However, the prevalence and dynamics of TAD-like...

FDA TechTalk podcast episode to focus on whole genome sequencing

FDA TECHTALK PODCAST EPISODE TO FOCUS ON WHOLE GENOME SEQUENCING

Nowadays, it seems rare to find someone or some entity without a podcast, and the Food and Drug Administration is no exception. The...

 
 
 

MEGALMM: MEGA-SCALE LINEAR MIXED MODELS FOR GENOMIC PREDICTIONS WITH THOUSANDS OF TRAITS

Large-scale phenotype data can enhance the power of genomic prediction in plant and animal breeding, as well as human genetics. However,...

After 40 Years, HIV Presents Research Problems New and Old

AFTER 40 YEARS, HIV PRESENTS RESEARCH PROBLEMS NEW AND OLD

In the years since AIDS was first described in medical research, the scientific map of that disease has changed enormously. Once it...

 
 
 

LOOKING INTO A COVID LUNG USING SPATIAL TRANSCRIPTOMICS

As the early weeks of the pandemic unfolded and health care workers struggled to save so many lives, researchers began tracking the...

PROGNOSTIC VALUE AND IMMUNOLOGICAL CHARACTERISTICS OF A NOVEL AUTOPHAGY-RELATED SIGNATURE IN PANCREATIC CANCER

Abstract Autophagy affects the development, progression, and prognosis of various cancers including pancreatic cancer. To develop an...

 
 
 
Sema4 goes public via SPAC merger

SEMA4 GOES PUBLIC VIA SPAC MERGER

With a goal of making precision medicine the standard of care at health systems, Sema4 struck a nearly $800 million deal with CM Life...

DEEPMIND AND EMBL RELEASE THE MOST COMPLETE DATABASE OF PREDICTED 3D STRUCTURES OF HUMAN PROTEINS

DeepMind today announced its partnership with the European Molecular Biology Laboratory , Europe's flagship laboratory for the life...

 
 
 

UNTWISTING DNA REVEALS NEW FORCE THAT SHAPES GENOMES

Advances in microscopy reveal how the human genome organises itself in three-dimensional space at much higher resolution than previously...

GENOME‐WIDE EPISTATIC INTERACTIONS OF LITTER SIZE AT BIRTH IN CHINESE INDIGENOUS PIGS

Summary Improving litter size at birth and the number of piglets born alive are the main breeding goals related to litter traits, which...

 
 
 

ACCURATE PREDICTION AND GENOME‐WIDE ASSOCIATION ANALYSIS OF DIGITAL INTRAMUSCULAR FAT CONTENT IN LONGISSIMUS MUSCLE OF PIGS

Summary Intramuscular fat content is a critical indicator of pork quality that affects directly the purchasing desire of consumers....

CHINESE SCIENTISTS PREDICT BRIGHT FUTURE FOR GENOME EDITED OIL CROPS

Scientists from China conducted a review on CRISPR technology and applications on oil crops to determine its prospects in the agricultural...

 
 
 

USING MACHINE-LEARNING TO FIND MUTATIONS IN SIMILAR GENOME SEQUENCES OF CANCER SAMPLES

A team of researchers working at the Francis Crick Institute has developed a way to find mutations in similar genome regions of cancer...

ARGININE METHYLATION IN GLOBAL CONTROL OF RNA SPLICING AND TRANSLATION

Thousands of proteins undergo arginine N-methylation, a widespread post-translational modification catalyzed by several protein arginine...

 
 
 

HAPLOFLOW: STRAIN-RESOLVED DE NOVO ASSEMBLY OF VIRAL GENOMES

EQTPLOT: A USER-FRIENDLY R PACKAGE FOR THE VISUALIZATION OF COLOCALIZATION BETWEEN EQTL AND GWAS SIGNALS

Genomic studies increasingly integrate expression quantitative trait loci information into their analysis pipelines, but few tools...

 
 
 

INACTIVATION OF THE GERMACRENE A SYNTHASE GENES BY CRISPR/CAS9 ELIMINATES THE BIOSYNTHESIS OF SESQUITERPENE LACTONES IN CICHORIUM INTYBUS L

Abstract Chicory is an industrial crop species cultivated for the production of a fructose polymer inulin which is used as a low calorie...

EXPANDING THE RANGE OF EDITABLE TARGETS IN THE WHEAT GENOME USING THE VARIANTS OF THE CAS12A AND CAS9 NUCLEASES

Abstract The development of CRISPR-based editors recognizing distinct protospacer adjacent motifs , or having different spacer length/structure...

 
 
 

TOWARDS ENGINEERING ECTOMYCORRHIZATION INTO SWITCHGRASS BIOENERGY CROPS VIA A LECTIN RECEPTOR‐LIKE KINASE

Abstract Soil-borne microbes can establish compatible relationships with host plants, providing a large variety of nutritive and protective...

Microbial Fingerprints for Cities

MICROBIAL FINGERPRINTS FOR CITIES

Co-author Russell Neches constructed this graphic and used it to examine the number of viruses and viral families that are shared among...