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Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by {alpha}-amanitin

Posted on: Mar 18, 2018   |   Posted by: Biotech Mag

RNA polymerase II is the central enzyme that transcribes eukaryotic protein-coding genes to produce mRNA. The mushroom toxin α-amanitin binds Pol II and inhibits transcription...