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MODEL BASED ON GA AND DNN FOR PREDICTION OF MRNA-SMAD7 EXPRESSION REGULATED BY MIRNAS IN BREAST CANCER

The Smad7 protein is negative regulator of the TGF-β signaling pathway, which is upregulated in patients with breast cancer. miRNAs...

 
 
 
15 For '19: Key Clinical Data to Watch For Next Year

15 FOR '19: KEY CLINICAL DATA TO WATCH FOR NEXT YEAR

On Monday, Xconomy began our annual look ahead at clinical trials that could define biotech and have profound healthcare effects in...

IDENTIFICATION AND CHARACTERIZATION OF DROUGHT RESPONSIVE MICRORNAS AND THEIR TARGET GENES IN CARDAMOM

Abstract Plant miRNAs are found to be present throughout the genome and they regulate gene expression either by cleaving mRNA or inhibiting...

 
 
 

INTEGRATED PROTEOTRANSCRIPTOMICS OF BREAST CANCER REVEALS GLOBALLY INCREASED PROTEIN-MRNA CONCORDANCE ASSOCIATED WITH SUBTYPES AND SURVIVAL

Abstract Background Transcriptome analysis of breast cancer discovered distinct disease subtypes of clinical significance. However,...

A PLUGIN FOR THE ENSEMBL VARIANT EFFECT PREDICTOR THAT USES MAXENTSCAN TO PREDICT VARIANT SPLICEOGENICITY

AbstractSummaryAssessing the pathogenicity of genetic variants can be a complex and challenging task. Spliceogenic variants, which...

 
 
 

BAYESIAN INFERENCE ON STOCHASTIC GENE TRANSCRIPTION FROM FLOW CYTOMETRY DATA

MotivationTranscription in single cells is an inherently stochastic process as mRNA levels vary greatly between cells, even for genetically...

MATATAKI: AN ULTRAFAST MRNA QUANTIFICATION METHOD FOR LARGE-SCALE REANALYSIS OF RNA-SEQ DATA

Data generated by RNA sequencing is now accumulating in vast amounts in public repositories, especially for human and mouse genomes....

 
 
 

TRANSLATE FILES FOR $115M IPO TO TRIAL EX-SHIRE MRNA CYSTIC FIBROSIS TREATMENT

Translate Bio has filed to raise $115 million from public investors. The IPO will tee Translate up to trial an mRNA candidate designed...

 
 
 

TRANSLATIONAL REGULATION OF RIBOSOMAL PROTEIN S15 DRIVES CHARACTERISTIC PATTERNS OF PROTEIN‐MRNA EPISTASIS

Proteins: Structure, Function, and Bioinformatics, EarlyView.

CRYO-EM STRUCTURE OF A MAMMALIAN RNA POLYMERASE II ELONGATION COMPLEX INHIBITED BY {ALPHA}-AMANITIN

RNA polymerase II is the central enzyme that transcribes eukaryotic protein-coding genes to produce mRNA. The mushroom toxin α-amanitin...

 
 
 

DEVELOPMENT OF AN IN VITRO PRE-MRNA SPLICING ASSAY USING PLANT NUCLEAR EXTRACT

Abstract Background Pre-mRNA splicing is an essential post-transcriptional process in all eukaryotes. In vitro splicing systems using...

MRNA ASSISTANT

Asst. Biologist/Biologist- BS/MS Immediate opening for a Molecular Biologist to assist in the development of novel PCR and other molecular...

 
 
 

ORTHODONTIC FORCE APPLICATION UPREGULATED PAIN-ASSOCIATED PROSTAGLANDIN-I 2 /PGI 2 -RECEPTOR/TRPV1 PATHWAY-RELATED GENE EXPRESSION IN RAT MOLARS

Abstract This study aimed to analyze the mRNA expression and protein localization of prostaglandin I 2 synthase , the PGI 2 receptor...

 
 
 
 
 
 
Eli Lilly to Pursue mRNA Cancer Vaccines with CureVac Pact

ELI LILLY TO PURSUE MRNA CANCER VACCINES WITH CUREVAC PACT

Eli Lilly is getting a foothold in messenger RNA cancer vaccines through a deal with CureVac that could develop up to five new therapies....

ASTRAZENECA INKS RESPIRATORY DISEASE MRNA PACT WITH ETHRIS 

AstraZeneca has expanded its mRNA activities through an agreement with Ethris. The Big Pharma is paying €25 million upfront to work...