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Tracking RNA to Pinpoint Time of Death: Better Than Bugs?

TRACKING RNA TO PINPOINT TIME OF DEATH: BETTER THAN BUGS?

DNA is a persistent molecule. Genome sequencing is possible for creatures as ancient as mummies and mammoths. But the messenger RNA...

INVESTIGATING THE THERAPEUTIC POTENTIAL AND MECHANISM OF CURCUMIN IN BREAST CANCER BASED ON RNA SEQUENCING AND BIOINFORMATICS ANALYSIS

Abstract Background Breast cancer is a prevalent cancer in female. This study aims to investigate the therapeutic potential and mechanism...

 
 
 

RNA STRUCTURE: A LASER-FOCUSED VIEW INTO CELLS

RNA structure: A LASER-focused view into cells RNA structure: A LASER-focused view into cells, Published online: 14 February 2018;...

LGC Acquires Lucigen, Marking Latest Exit for CEO Ralph Kauten

LGC ACQUIRES LUCIGEN, MARKING LATEST EXIT FOR CEO RALPH KAUTEN

Chalk up another exit for Ralph Kauten. Kauten, one of Wisconsin's more successful biotech entrepreneurs, is chairman and CEO of Lucigen,...

 
 
 
Patients With Huntington's Disease Less Likely to Get Cancer

PATIENTS WITH HUNTINGTON'S DISEASE LESS LIKELY TO GET CANCER

Repeating RNA sequence attack in Huntington's disease attack the brain cells and are found to be toxic for the cancer cells to survive.

HIERARCHICAL ANALYSIS OF RNA-SEQ READS IMPROVES THE ACCURACY OF ALLELE-SPECIFIC EXPRESSION

AbstractMotivationAllele-specific expression refers to the differential abundance of the allelic copies of a transcript. RNA sequencing...

 
 
 

A NOVEL RIBOREGULATOR SWITCH SYSTEM OF GENE EXPRESSION FOR ENHANCED MICROBIAL PRODUCTION OF SUCCINIC ACID

Abstract In this paper, a novel riboregulator Switch System of Gene Expression including an OFF-TO-ON switch and an ON-TO-OFF switch...

PARTIAL DNA-GUIDED CAS9 ENABLES GENOME EDITING WITH REDUCED OFF-TARGET ACTIVITY

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity Partial DNA-guided Cas9 enables genome editing with...

 
 
 

METHOD TO PRECISELY DETERMINE WHEN CELL HAS 'CASHED' RNA 'CHECKS' WRITTEN BY ACTIVE GENES

Scientists have designed software that enables biologists to determine with unprecedented accuracy how much protein a given cell is...

 
 
 

NOVEL CHIP-BASED GENE EXPRESSION TOOL ANALYZES RNA QUICKLY AND ACCURATELY

A University of Illinois and Mayo collaboration has demonstrated a novel gene expression analysis technique that can accurately measure...

TUNING ITERATION SPACE SLICING BASED TILED MULTI-CORE CODE IMPLEMENTING NUSSINOV'S RNA FOLDING

RNA folding is an ongoing compute-intensive task of bioinformatics. Parallelization and improving code locality for this kind of algorithms...

 
 
 

BI-OBJECTIVE INTEGER PROGRAMMING FOR RNA SECONDARY STRUCTURE PREDICTION WITH PSEUDOKNOTS

RNA structure prediction is an important field in bioinformatics, and numerous methods and tools have been proposed. Pseudoknots are...

 
 
 

DEVELOPMENT OF AN IN VITRO PRE-MRNA SPLICING ASSAY USING PLANT NUCLEAR EXTRACT

Abstract Background Pre-mRNA splicing is an essential post-transcriptional process in all eukaryotes. In vitro splicing systems using...

DISCOVERING THE STRUCTURE OF RNA

A research team has developed a computerized simulation model which can effectively predict the three-dimensional conformation of the...

 
 
 

UPSTART EXPANSION BAGS A $55M LAUNCH ROUND TO JOIN THE HUNT FOR RNA-TARGETING SMALL MOLECULES

Arrakis isn't the only biotech startup looking to develop RNA-targeted small molecule drugs. Now they have a rival in Expansion Therapeutics,...

ENTEROVIRUS-ASSOCIATED CHANGES IN BLOOD TRANSCRIPTOMIC PROFILES OF CHILDREN WITH GENETIC SUSCEPTIBILITY TO TYPE 1 DIABETES

Abstract Aims/hypothesis Enterovirus infections have been associated with the development of type 1 diabetes in multiple studies, but...

 
 
 

AN EXPLORATION INTO THE BACTERIAL COMMUNITY UNDER DIFFERENT PASTEURIZATION CONDITIONS DURING SUBSTRATE PREPARATION FOR AGARICUS BISPORUS CULTIVATION

Abstract Substrate preparation for Agaricus bisporus cultivation is the most critical point of mushroom production. Among many factors...

FINE MAPPING AND CANDIDATE GENE ANALYSIS OF THE QUANTITATIVE TRAIT LOCUS GW8.1 ASSOCIATED WITH GRAIN LENGTH IN RICE

Abstract A quantitative trait locus gw8.1 was detected in the population derived from a cross between the elite japonica cultivar,...