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PROFILING THE GENOME HUNDREDS OF VARIATIONS AT A TIME

Geneticists have been using model organisms ranging from the house mouse to the single-cell bakers' yeast, Saccharomyces cerevisiae,...

VERGE GENOMICS ANNOUNCES LANDMARK EFFORT TO GENERATE FIELD'S FIRST SINGLE CELL DATA FROM PATIENTS WITH PARKINSON'S DISEASE

In partnership with UC San Diego and VIB, Verge Genomics is leading an industry-academic consortium that will be the first to sequence...

 
 
 
Maria Boftsi IAmScience

MARIA BOFTSI IAMSCIENCE

Maria Boftsi, a Ph. D candidate, stands near her lab station in the Pintel Lab in Bond LSC. | photo by Allison Scott, Bond LSC By Allison...

 
 
 
10,000 tumors, 33 types of cancer: The PanCancer Atlas

10,000 TUMORS, 33 TYPES OF CANCER: THE PANCANCER ATLAS

Chen Wang, Ph.D. The National Institutes of Health PanCancer Atlas is an in-depth genomic analysis that includes a collection of 27...

Living Large: Exploration of Diverse Bacteria Signals Big Advance for Gene Function Prediction

LIVING LARGE: EXPLORATION OF DIVERSE BACTERIA SIGNALS BIG ADVANCE FOR GENE FUNCTION PREDICTION

By Massie Santos Ballon In the air, beneath the ocean's surface, and on land, microbes are the minute but mighty forces regulating...

 
 
 
Disease-Causing LINE-1 Insertions: Rare or Just Hard to Spot?

DISEASE-CAUSING LINE-1 INSERTIONS: RARE OR JUST HARD TO SPOT?

Patient's muscle biopsy - Hematoxylin and eosin stain shows severe fibrosis and fat substitution. Arrow indicates a necrotic fiber. LINE-1...

 
 
 
Celsius Snags $65M to Harness Single-Cell Genomics for Drug Discovery

CELSIUS SNAGS $65M TO HARNESS SINGLE-CELL GENOMICS FOR DRUG DISCOVERY

With biotech flush with venture capital funding, it seems that every hot new area of biology research now comes with its own startup....

“Wrong to Toast”: Broad's Lander Sorry for Tribute to DNA Pioneer Watson

“WRONG TO TOAST”: BROAD'S LANDER SORRY FOR TRIBUTE TO DNA PIONEER WATSON

Amid backlash, renowned geneticist Eric Lander, the Broad Institute president and founding director, apologized today for his toast...

 
 
 
Codfish Study Employs Target Capture and SMRT Sequencing to Explore Evolution

CODFISH STUDY EMPLOYS TARGET CAPTURE AND SMRT SEQUENCING TO EXPLORE EVOLUTION

Many investigators rely on targeted sequencing approaches for deep dives into genomic regions of interest. By designing specific probes...

PROTECTING CONFIDENTIALITY IN GENOMIC STUDIES

Genome-wide association studies, which look for links between particular genetic variants and incidence of disease, are the basis of...

 
 
 
Introduction of the Iso-Seq Method: State of the Art for Full-Length Transcriptome Sequencing

INTRODUCTION OF THE ISO-SEQ METHOD: STATE OF THE ART FOR FULL-LENGTH TRANSCRIPTOME SEQUENCING

Photo by John Cobb on Unsplash In eukaryotic organisms, the majority of genes are alternatively spliced to produce multiple transcript...

4 Berkeley Lab-affiliated Scientists Elected as National Academy of Sciences Members

4 BERKELEY LAB-AFFILIATED SCIENTISTS ELECTED AS NATIONAL ACADEMY OF SCIENCES MEMBERS

Four scientists affiliated with the U.S. Department of Energy's Lawrence Berkeley National Laboratory are among the group of 84 new...

 
 
 
An Interview with Baylor's Fritz Sedlazeck on New Long-Read Algorithms

AN INTERVIEW WITH BAYLOR'S FRITZ SEDLAZECK ON NEW LONG-READ ALGORITHMS

Fritz Sedlazeck Nature Methods just published “ Accurate detection of complex structural variations using single-molecule sequencing...

UNIVERSAL EVOLUTIONARY SELECTION FOR HIGH DIMENSIONAL SILENT PATTERNS OF INFORMATION HIDDEN IN THE REDUNDANCY OF VIRAL GENETIC CODE

AbstractMotivationUnderstanding how viruses co-evolve with their hosts and adapt various genomic level strategies in order to ensure...

 
 
 
60 Minutes Shines Spotlight on the Power and Promise of CRISPR

60 MINUTES SHINES SPOTLIGHT ON THE POWER AND PROMISE OF CRISPR

On Sunday night, 60 Minutes ran a captivating segment on the promise and possibilities of CRISPR - the revolutionary, cutting-edge...

E. coli-infected salad saga rages on: 31 more sickened, bringing the total to 84

E. COLI-INFECTED SALAD SAGA RAGES ON: 31 MORE SICKENED, BRINGING THE TOTAL TO 84

E. coli linked to romaine lettuce has now sickened 84 people across the US. The CDC says the germ came from Arizona, but it is using...

 
 
 
Nature Webinar and SMRT Grant Winner Explore Structural Variation for Disease Gene Discovery

NATURE WEBINAR AND SMRT GRANT WINNER EXPLORE STRUCTURAL VARIATION FOR DISEASE GENE DISCOVERY

Structural variants account for most of the base pairs that differ between human genomes, and are known to cause more than 1,000 genetic...