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Bananas Are on the Brink of Extinction. Gene Editing Can Reverse That

BANANAS ARE ON THE BRINK OF EXTINCTION. GENE EDITING CAN REVERSE THAT

Since the 1950s the Cavendish variety has held a monopoly on the banana market. But its dominance is not the result of taste or preference....

RIP Kary Mullis, Father of PCR

RIP KARY MULLIS, FATHER OF PCR

When the name Kary Mullis popped up in my news feed on Monday, I was excited to read what I thought would be an update on the renegade...

 
 
 

LSX: AUTOMATED REDUCTION OF GENE-SPECIFIC LINEAGE EVOLUTIONARY RATE HETEROGENEITY FOR MULTI-GENE PHYLOGENY INFERENCE

Lineage rate heterogeneity can be a major source of bias, especially in multi-gene phylogeny inference. We had previously tackled this...

GENETIC CENSUS OF THE HUMAN MICROBIOME

Scientists have analyzed the genetic repertoire of bacteria in the human mouth and gut. The effort marks the first chapter in efforts...

 
 
 

YANAGI: FAST AND INTERPRETABLE SEGMENT-BASED ALTERNATIVE SPLICING AND GENE EXPRESSION ANALYSIS

Ultra-fast pseudo-alignment approaches are the tool of choice in transcript-level RNA sequencing analyses. Unfortunately, these methods...

TREATING GLIOBLASTOMA WITH A ZIOPHARM DRUG AND IL-12 GENE THERAPY

A phase 1 clinical trial in glioblastoma involving Ziopharm Oncology suggests that controlling the production of human IL-12 using...

 
 
 
Gene that 'protects against Alzheimer's' could lead to 'new treatments for the disease'

GENE THAT 'PROTECTS AGAINST ALZHEIMER'S' COULD LEAD TO 'NEW TREATMENTS FOR THE DISEASE'

Scientists at Washington University in St Louis analysed spinal fluid samples from around 800 participants. Some had the memory-robbing...

NEW INSIGHTS INTO THE MECHANISM OF VACCINE-INDUCED T CELL IMMUNITY

Medical researchers have gained new insights into the mechanism of vaccine-induced T cell immunity, including regulation, gene expression...

 
 
 

BIOLOGISTS PIONEER FIRST METHOD TO DECODE GENE EXPRESSION

Biologists have developed the first system for determining gene expression based on machine learning. Considered a type of genetic...

REVOLUTIONISING THE CRISPR METHOD

Everyone's talking about CRISPR-Cas. This biotechnological method offers a relatively quick and easy way to manipulate single genes...

 
 
 
Your microbiome may have 'more genes than the universe has stars,' study finds

YOUR MICROBIOME MAY HAVE 'MORE GENES THAN THE UNIVERSE HAS STARS,' STUDY FINDS

A new study from Harvard Medical School has found there could be anywhere from 232 million genes in the human microbiome to as many...

EPIP: A NOVEL APPROACH FOR CONDITION-SPECIFIC ENHANCER-PROMOTER INTERACTION PREDICTION

AbstractMotivationThe identification of enhancer-promoter interactions especially cell-specific ones is important for the study of...

 
 
 

PINPOINTING THE MOLECULAR MECHANISMS OF AGEING

Although each and every one of us goes through it, ageing is a poorly understood process. Researchers have used a biomarker called...

OXIDATIVE STRESS UNDER LOW OXYGEN CONDITIONS TRIGGERS HYPERFLAGELLATION AND MOTILITY IN THE ANTARCTIC BACTERIUM PSEUDOMONAS EXTREMAUSTRALIS

Abstract Reactive oxygen species and nitrogen species , produced in a wide range of physiological process even under low oxygen availability,...

 
 
 

ANALYSIS OF VIBRIO CHOLERAE GENOMES IDENTIFIES NEW TYPE VI SECRETION SYSTEM GENE CLUSTERS

Like many bacteria, Vibrio cholerae deploys a harpoon-like type VI secretion system to compete against other microbes in environmental...

RECOMBINANT PRODUCTION AND CHARACTERIZATION OF A NOVEL ESTERASE FROM A HYPERSALINE LAKE, ACIGÖL, BY METAGENOMIC APPROACH

Abstract The aim of this study was to isolate a novel esterase from a hypersaline lake by sequence-based metagenomics. The metagenomic...

 
 
 

GENE FOR ACID-SENSITIVE ION CHANNEL IDENTIFIED

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels...

DEVELOPING A MULTI-DOSE COMPUTATIONAL MODEL FOR DRUG-INDUCED HEPATOTOXICITY PREDICTION BASED ON TOXICOGENOMICS DATA

Drug-induced hepatotoxicity may cause acute and chronic liver disease, leading to great concern for patient safety. It is also one...

 
 
 

HUMAN PATHWAY-BASED DISEASE NETWORK

Constructing disease-disease similarity network is important in elucidating the associations between the origin and molecular mechanism...

CONTROL OF GENE REGULATORY NETWORKS USING BAYESIAN INVERSE REINFORCEMENT LEARNING

Control of gene regulatory networks to shift gene expression from undesirable states to desirable ones has received much attention...