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RIBOMINER: A TOOLSET FOR MINING MULTI-DIMENSIONAL FEATURES OF THE TRANSLATOME WITH RIBOSOME PROFILING DATA

Ribosome profiling has been widely used for studies of translation under a large variety of cellular and physiological contexts. Many...

MUTENRICHER: A FLEXIBLE TOOLSET FOR SOMATIC MUTATION ENRICHMENT ANALYSIS OF TUMOR WHOLE GENOMES

Analysis of somatic mutations from tumor whole exomes has fueled discovery of novel cancer driver genes. However, ~ 98% of the genome...

 
 
 

A NOVEL WICK‐LIKE PAPER‐BASED MICROFLUIDIC DEVICE FOR 3D CELL CULTURE AND ANTI‐CANCER DRUGS SCREENING

Paper is increasingly recognized as a unique and portable substrate for cell culture, due to its low‐cost, tunable, flexible and special...

Study: Euromed's ABAlife fig extract promotes muscle metabolism and insulin sensitivity

STUDY: EUROMED'S ABALIFE FIG EXTRACT PROMOTES MUSCLE METABOLISM AND INSULIN SENSITIVITY

Abscisic acid works synergistically with insulin to improve cellular glucose uptake while decreasing obesity related systemic inflammation,...

 
 
 

EMBRYONIC GENE EXPRESSION ALTERED BY MATERNAL EXPOSURE TO AIR POLLUTION IN RATS

Abstract Exposure to air pollution is known to increase the risks for cardiovascular, pulmonary and metabolic diseases. Growing evidences...

Google Stadia's latest experiment adds support for gaming on 5G

GOOGLE STADIA'S LATEST EXPERIMENT ADDS SUPPORT FOR GAMING ON 5G

Google Stadia, the cloud-based game streaming service, requires a fast network to support the type of low-latency gameplay subscribers...

 
 
 

FEW SHOT DOMAIN ADAPTATION FOR IN SITU MACROMOLECULE STRUCTURAL CLASSIFICATION IN CRYO-ELECTRON TOMOGRAMS

AbstractMotivationCryo-Electron Tomography visualizes structure and spatial organization of macromolecules and their interactions with...

BAYESIAN MODEL SELECTION REVEALS BIOLOGICAL ORIGINS OF ZERO INFLATION IN SINGLE-CELL TRANSCRIPTOMICS

Single-cell RNA sequencing is a powerful tool for characterizing cellular heterogeneity in gene expression. However, high variability...

 
 
 

BIOLOGISTS SHED LIGHT ON HOW CELLS MOVE RESOURCES

Researchers have new insight into the tiny packages that cells use to move molecules, a structure that is key to cellular metabolism,...

SURVIVIN IN BREAST CANCER-DERIVED EXOSOMES ACTIVATES FIBROBLASTS BY UPREGULATING SOD1, WHOSE FEEDBACK PROMOTES CANCER PROLIFERATION AND METASTASIS

Cancer-associated fibroblasts play a critical role in the coevolution of breast tumor cells and their microenvironment by modifying...

 
 
 

THE SCIFF‐DERIVED RANTHIPEPTIDES PARTICIPATE IN QUORUM SENSING IN SOLVENTOGENIC CLOSTRIDIA

Abstract Ranthipeptides, defined as radical non‐α thioether‐containing peptides, are a newly emerging class of natural products belonging...

A NOVEL KNOCK OUT STRATEGY TO ENHANCE RECOMBINANT PROTEIN EXPRESSION IN ESCHERICHIA COLI

The expression of recombinant proteins triggers a stress response which downregulates key metabolic pathway genes leading to a decline...

 
 
 
T-Mobile Customers May Need A New 4G VoLTE Phone By January 2021

T-MOBILE CUSTOMERS MAY NEED A NEW 4G VOLTE PHONE BY JANUARY 2021

Internal documents suggest that T-Mobile will require many of its customers to buy new a new phone by January 2021. The documents,...

SMART NANOCARRIERS FOR THE DELIVERY OF NUCLEIC ACID‐BASED THERAPEUTICS: A COMPREHENSIVE REVIEW

Abstract Background : Nucleic acid‐based therapies are promising therapeutics for the treatment of several systemic disorders, and...

 
 
 

RAMAN‐BASED DYNAMIC FEEDING STRATEGIES USING REAL‐TIME GLUCOSE CONCENTRATION MONITORING SYSTEM DURING ADALIMUMAB PRODUCING CHO CELL CULTIVATION

Abstract The use of Process Analytical Technology tools coupled with chemometrics has been shown great potential for better understanding...

 
 
 
Roche, Jnana Enter Drug R&D Alliance Targeting Metabolism's Gatekeepers

ROCHE, JNANA ENTER DRUG R&D ALLIANCE TARGETING METABOLISM'S GATEKEEPERS

Scientists know that proteins called solute carrier transporters move substances important to metabolism across cellular membranes....

ENGINEERING TRANSCRIPTION FACTOR-BASED BIOSENSORS FOR REPRESSIVE REGULATION THROUGH TRANSCRIPTIONAL DEACTIVATION DESIGN IN SACCHAROMYCES CEREVISIAE

With the development of engineering the microbial cell factories, biosensors have been used widely for regulation of cellular metabolism...

 
 
 

SPECIALIZED CELLULAR COMPARTMENTS DISCOVERED IN BACTERIA

Researchers have discovered bacterial organelles involved in gene expression, suggesting that bacteria may not be as simple as once...

POTASSIUM CHANNEL KCN11 IS REQUIRED FOR MAINTAINING CELLULAR OSMOLARITY DURING NITROGEN STARVATION TO CONTROL PROPER CELL PHYSIOLOGY AND TAG ACCUMULATION IN CHLAMYDOMONAS REINHARDTII

Nitrogen starvation in algae induces a variety of structural and metabolic changes including accumulation of triacylglycerol. Given...