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RESEARCHERS DEMONSTRATE DOUBLE-LOCK PROTECTION MECHANISM IN CRUCIAL CELLULAR SWITCHES

Ludwig-Maximilians-Universitaet in Munich researchers have used CRISPR technology to probe the mechanisms that guide the developmental...

Laurie Glimcher To Headline Xconomy Keynote Series in Boston in September

LAURIE GLIMCHER TO HEADLINE XCONOMY KEYNOTE SERIES IN BOSTON IN SEPTEMBER

As groundbreaking therapies and diagnostics are coming to market, more patients are benefiting from the promise of precision medicine,...

 
 
 

FREQUENCY OF OFF-TARGETING IN GENOME EDITED PIGS PRODUCED VIA DIRECT INJECTION OF THE CRISPR/CAS9 SYSTEM INTO DEVELOPING EMBRYOS

The CRISPR/Cas9 system can effectively introduce site-specific modifications to the genome. The efficiency is high enough to induce...

 
 
 

ROBUST CRISPR/CPF1 MEDIATED GENOME EDITING IN ALLOTETRAPLOID COTTON

Abstract As an allotetraploid, most genes have multiple copies that belong to At and Dt subgenomes in cotton. Different types of gene...

CSESA: AN R PACKAGE TO PREDICT SALMONELLA ENTERICA SEROTYPE BASED ON NEWLY INCORPORATED SPACER PAIRS OF CRISPR

Salmonella enterica is a major cause of bacterial food-borne disease worldwide. Immunological serotyping is the most commonly used...

 
 
 

GENOME SEQUENCING AND CRISPR/CAS9 GENE EDITING OF AN EARLY FLOWERING MINI CITRUS

Summary Hongkong kumquat is a wild citrus species characterized by dwarf plant height and early flowering. Here, we identified the...

Bio Roundup: Nationwide's Rise, a Surgeon's Quest, CRISPR USA & More

BIO ROUNDUP: NATIONWIDE'S RISE, A SURGEON'S QUEST, CRISPR USA & MORE

Persistence and perseverance were the themes of two of our top stories this week. First there's the story of Nationwide Children's...

 
 
 

CIBUS ISSUED NEW PATENT COVERING ITS GENE-EDITING TECHNOLOGIES IN PLANTS

Patent Extends Intellectual Property for its RTDS Technologies in combination with CRISPRs - SAN DIEGO, April 8, 2019 /PRNewswire/...

Positive Gene Editing for Sickle Cell Disease and Beta Thalassemia

POSITIVE GENE EDITING FOR SICKLE CELL DISEASE AND BETA THALASSEMIA

New approach to gene editing for major blood disorders such as sickle cell disease and beta-thalassemia has been optimized. CRISPR-Cas9...

 
 
 
New CRISPR-powered Device Can Detect Genetic Mutations in Minutes

NEW CRISPR-POWERED DEVICE CAN DETECT GENETIC MUTATIONS IN MINUTES

New CRISPR-powered device can help identify genetic mutations in a matter of minutes. Therefore, the new hand-held device could be...

OPTIMIZING A CRISPR-CPF1-BASED GENOME ENGINEERING SYSTEM FOR CORYNEBACTERIUM GLUTAMICUM

Corynebacterium glutamicum is an important industrial strain for the production of a diverse range of chemicals. Cpf1 nucleases are...

 
 
 

CRISPR‐LBCAS12A‐MEDIATED MODIFICATION OF CITRUS

Abstract Recently, CRISPR‐Cas12a from Prevotella and Francisella was engineered to modify plant genomes. In this report, we employed...

NEW CRISPR-POWERED DEVICE DETECTS GENETIC MUTATIONS IN MINUTES

A team of engineers at the University of California, Berkeley and the Keck Graduate Institute of The Claremont Colleges combined CRISPR...

 
 
 
Bio Roundup: Golumbeski's Legacy, CRISPR Moratorium, Rebate Week & More

BIO ROUNDUP: GOLUMBESKI'S LEGACY, CRISPR MORATORIUM, REBATE WEEK & MORE

While all eyes in the biopharmaceutical world are currently trained on Bristol-Myers Squibb's proposal to buy Celgene for $74 billion...

SNIPR RAISES $50M TO USE CRISPR TO MODULATE THE MICROBIOME

Snipr Biome has raised $50 million to take CRISPR-based microbiome drugs into clinical trials. The Danish biotech is using CRISPR/Cas...

 
 
 

ILLUMINATING THE GENOME

The CRISPR/Cas9 system has been causing ripples in the scientific community ever since its mechanisms were reported in 2012. Commonly...

Beam Brings In $135M to Turn CRISPR Base Editing into Drugs

BEAM BRINGS IN $135M TO TURN CRISPR BASE EDITING INTO DRUGS

Beam Therapeutics made a splash last year when it launched with $87 million to develop medicines that use a more precise form of CRISPR...

 
 
 

CHECKING DNA BASE EDITOR'S MISTAKES AND TRICKS TO REDUCE THEM

Scientists have identified the mistake-rate of DNA editing tools, based on CRISPR and known as adenine base editors. Assessing the...

BOYCE THOMPSON INSTITUTE LAUNCHES NEW PLANT GENOME EDITING DATABASE

Recently developed gene editing tools like CRISPR/Cas enable plant scientists to figure out the functions of myriad plant genes. While...