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CIRCULATING MIR-3659 MAY BE A POTENTIAL BIOMARKER OF DYSLIPIDEMIA IN PATIENTS WITH OBESITY

Abstract Background The present study attempted to identify potential key genes and miRNAs of dyslipidemia in obese, and to investigate...

ITRAQ-BASED PROTEOMIC ANALYSIS OF RESPONSES OF LACTOBACILLUS PLANTARUM FS5-5 TO SALT TOLERANCE

Abstract Lactobacillus plantarum FS5-5 is a salt-tolerant probiotic strain, which had been isolated from northeast Chinese traditionally...

 
 
 

SIAN: SOFTWARE FOR STRUCTURAL IDENTIFIABILITY ANALYSIS OF ODE MODELS

AbstractSummaryBiological processes are often modeled by ordinary differential equations with unknown parameters. The unknown parameters...

THE IMPACT OF THE FECAL MICROBIOME ON CANCER IMMUNOTHERAPY

Abstract Recent advances in culture-free methods of studying the human microbiome, coupled with strong bioinformatics tools, have provided...

 
 
 

A BENCHMARK STUDY OF SEQUENCE ALIGNMENT METHODS FOR PROTEIN CLUSTERING

Protein sequence alignment analyses have become a crucial step for many bioinformatics studies during the past decades. Multiple sequence...

MULTIVIEW: A SOFTWARE PACKAGE FOR MULTIVIEW PATTERN RECOGNITION METHODS

AbstractSummaryMultiview datasets are the norm in bioinformatics, often under the label multi-omics. Multiview data is gathered from...

 
 
 

BIOINFORMATICS TOOLS TO ASSESS METAGENOMIC DATA FOR APPLIED MICROBIOLOGY

Abstract The reduction of the price of DNA sequencing has resulted in the emergence of large data sets to handle and analyze, especially...

SELECTIVE AND FASTER NICOTINE BIODEGRADATION BY GENETICALLY MODIFIED PSEUDOMONAS SP. JY-Q IN THE PRESENCE OF GLUCOSE

Abstract Pseudomonas sp. JY-Q is a nicotine-degrading strain isolated from tobacco waste extract. In TWE, the nicotine is a toxic chemical...

 
 
 

WHOLE-EXOME SEQUENCING IDENTIFIED A NOVEL MUTATION OF AURKC IN A CHINESE FAMILY WITH MACROZOOSPERMIA

Abstract Purpose Macrozoospermia is a rare sperm morphologic abnormality associated with male infertility and is characterized by a...

THE INTERNATIONAL CONFERENCE ON INTELLIGENT BIOLOGY AND MEDICINE 2018: BIOINFORMATICS TOWARDS TRANSLATIONAL APPLICATIONS

The 2018 International Conference on Intelligent Biology and Medicine was held on June 10-12, 2018, in Los Angeles, California, USA....

 
 
 

ACE: ABSOLUTE COPY NUMBER ESTIMATION FROM LOW-COVERAGE WHOLE-GENOME SEQUENCING DATA

AbstractSummaryChromosomal copy number aberrations can be efficiently detected and quantified using low-coverage whole-genome sequencing...

UNDERSTANDING METABOLIC PROCESSES THROUGH MACHINE LEARNING

Bioinformatics researchers at Heinrich Heine University Düsseldorf and the University of California at San Diego are using machine...

 
 
 

TNF-ALPHA AND METALLOPROTEASES AS KEY PLAYERS IN MELANOMA CELLS AGGRESSIVENESS

Abstract Background Melanoma aggressiveness determines its growth and metastatic potential. This study aimed at identifying new molecular...

REPLY TO THE PAPER: MISUNDERSTOOD PARAMETERS OF NCBI BLAST IMPACTS THE CORRECTNESS OF BIOINFORMATICS WORKFLOWS

 
 
 

PCONSC4: FAST, ACCURATE, AND HASSLE-FREE CONTACT PREDICTIONS

AbstractMotivationResidue contact prediction was revolutionized recently by the introduction of direct coupling analysis. Further improvements,...

COMPUTING IRREVERSIBLE MINIMAL CUT SETS IN GENOME-SCALE METABOLIC NETWORKS VIA FLUX CONE PROJECTION

AbstractMotivationMinimal cut sets for metabolic networks are sets of reactions which, if they are removed from the network, prevent...

 
 
 

M3DROP: DROPOUT-BASED FEATURE SELECTION FOR SCRNASEQ

AbstractMotivationMost genomes contain thousands of genes, but for most functional responses, only a subset of those genes are relevant....

SMOOTH ORIENTATION-DEPENDENT SCORING FUNCTION FOR COARSE-GRAINED PROTEIN QUALITY ASSESSMENT

AbstractMotivationProtein quality assessment is a crucial element of protein structure prediction, a fundamental and yet open problem...

 
 
 

APPLICATION OF MICROSATELLITE GENOTYPING BY SEQUENCING TO MEASURE GENETIC DIVERSITY OF THE EAST AFRICAN OREOCHROMIS NILOTICUS

Abstract Microsatellites play an important role when investigating population and ecological genetics, although high effort in development...

ALIGNMENT-FREE GENOME COMPARISON ENABLES ACCURATE GEOGRAPHIC SOURCING OF WHITE OAK DNA

Abstract Background The application of genomic data and bioinformatics for the identification of restricted or illegally-sourced natural...