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LONG-CHAIN VITAMIN K2 PRODUCTION IN LACTOCOCCUS LACTIS IS INFLUENCED BY TEMPERATURE, CARBON SOURCE, AERATION AND MODE OF ENERGY METABOLISM

Vitamin K2 is a lipid-soluble vitamin that functions as a carboxylase co-factor for maturation of proteins involved in many vital physiological...

CHARACTERIZATION OF AN ACETYL XYLAN ESTERASE FROM THE MARINE BACTERIUM OCHROVIRGA PACIFICA AND ITS SYNERGISM WITH XYLANASE ON BEECHWOOD XYLAN

Acetyl xylan esterase plays an important role in the complete enzymatic hydrolysis of lignocellulosic materials. It hydrolyzes the...

 
 
 

GENOME-SCALE NETWORK MODEL OF METABOLISM AND HISTONE ACETYLATION REVEALS METABOLIC DEPENDENCIES OF HISTONE DEACETYLASE INHIBITORS

Histone acetylation plays a central role in gene regulation and is sensitive to the levels of metabolic intermediates. However, predicting...

HETEROLOGOUS PHOSPHOKETOLASE EXPRESSION REDIRECTS FLUX TOWARDS ACETATE, PERTURBS SUGAR PHOSPHATE POOLS AND INCREASES RESPIRATORY DEMAND IN SACCHAROMYCES CEREVISIAE

Phosphoketolases are a non-native group of enzymes in yeast, which can be expressed in combination with other metabolic enzymes to...

 
 
 

OSACL‐A2 NEGATIVELY REGULATES CELL DEATH AND DISEASE RESISTANCE IN RICE

Summary ATP‐citrate lyases play critical roles in tumor cell propagation, fetal development and growth, and histone acetylation in...

ENHANCED TRIACYLGLYCEROL PRODUCTION IN THE DIATOM PHAEODACTYLUM TRICORNUTUM BY INACTIVATION OF A HOTDOG-FOLD THIOESTERASE GENE USING TALEN-BASED TARGETED MUTAGENESIS

In photosynthetic oleaginous microalgae, acyl-CoA molecules are used as substrates for the biosynthesis of membrane glycerolipids,...

 
 
 

NATURAL SEPARATION OF THE ACYL-COA LIGASE REACTION RESULTS IN A NON-ADENYLATING ENZYME

Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme Natural separation of the acyl-CoA ligase reaction...

 
 
 

PROACEPRED: PROKARYOTE LYSINE ACETYLATION SITES PREDICTION BASED ON ELASTIC NET FEATURE OPTIMIZATION

AbstractMotivationLysine acetylation exists extensively in prokaryotes, and plays a vital role in function adjustment. Recent progresses...

 
 
 

BIOSYNTHESIS OF ANGELYL-COA IN SACCHAROMYCES CEREVISIAE

The angelic acid moiety represents an essential modification in many biologically active products. These products are commonly known...

RE-DIRECTION OF CARBON FLUX TO KEY PRECURSOR MALONYL-COA VIA ARTIFICIAL SMALL RNAS IN PHOTOSYNTHETIC SYNECHOCYSTIS SP. PCC 6803

Photosynthetic cyanobacteria have attracted a significant attention as promising chassis to produce renewable fuels and chemicals due...

 
 
 
L-Carnitine Benefits Endurance, Fat Burning & Brain Function

L-CARNITINE BENEFITS ENDURANCE, FAT BURNING & BRAIN FUNCTION

By Rachael Link, MS, RD Let's face it: Amino acids are crucial to pretty much every aspect of health. These compounds are the building...

OVEREXPRESSION OF A DOMAIN OF UNKNOWN FUNCTION 231-CONTAINING PROTEIN INCREASES O-XYLAN ACETYLATION AND CELLULOSE BIOSYNTHESIS IN POPULUS

Domain of Unknown Function 231-containing proteins are plant specific and their function is largely unknown. Studies in the model plants...

 
 
 

TWO BIFUNCTIONAL ENZYMES FROM THE MARINE PROTIST THRAUSTOCHYTRIUM ROSEUM: BIOCHEMICAL CHARACTERIZATION OF WAX ESTER SYNTHASE/ACYL-COA:DIACYLGLYCEROL ACYLTRANSFERASE ACTIVITY CATALYZING WAX ESTER AND TRIACYLGLYCEROL SYNTHESIS

Triacylglycerols and wax esters are important neutral lipids which serve as energy reservoir in some plants and microorganisms. In...

THE SIALATE O-ACETYLESTERASE ESTA FROM GUT BACTEROIDETES SPECIES ENABLES SIALIDASE-MEDIATED CROSS-SPECIES FORAGING OF 9-O-ACETYLATED SIALOGLYCANS

The gut harbors many symbiotic, commensal, and pathogenic microbes that engage in the breakdown and metabolism of host carbohydrates....

 
 
 

CHO CELLS ADAPTED TO INORGANIC PHOSPHATE LIMITATION SHOW HIGHER GROWTH AND HIGHER PYRUVATE CARBOXYLASE FLUX IN PHOSPHATE REPLETE CONDITIONS

Abstract Inorganic phosphate is an essential ion involved in diverse cellular processes including metabolism. Changes in cellular metabolism...

INCREASING N-BUTANOL PRODUCTION WITH SACCHAROMYCES CEREVISIAE BY OPTIMIZING ACETYL-COA SYNTHESIS, NADH LEVELS AND TRANS-2-ENOYL-COA REDUCTASE EXPRESSION

N-Butanol can serve as an excellent gasoline substitute. Naturally, it is produced by some Clostridia species which, however, exhibit...

 
 
 

ANAEROBIC POLY-3-D-HYDROXYBUTYRATE PRODUCTION FROM XYLOSE IN RECOMBINANT SACCHAROMYCES CEREVISIAE USING A NADH-DEPENDENT ACETOACETYL-COA REDUCTASE

Poly-3-d-hydroxybutyrate that is a promising precursor for bioplastic with similar physical properties as polypropylene, is naturally...

N-acetyl-cysteine Drug may Help Prevent Age-related Health Problems

N-ACETYL-CYSTEINE DRUG MAY HELP PREVENT AGE-RELATED HEALTH PROBLEMS

N-acetyl-cysteine or NAC drug may prevent many age-related health problems when used at much lower levels, suggests new research conducted...